STEVENSON, Wash.–(BUSINESS WIRE)–Total Nutraceutical Solutions, Inc. (TNS) (OTCBB:TNUS) announced today that the company has acquired from The Penn State Research Foundation (PSRF) an exclusive license agreement on the invention (the “Invention”) entitled “Methods and Compositions for Improving the Nutritional Content of Mushrooms and Fungi.” This invention is covered by the United States Patent Application No. 12/386,810, filed on April 23, 2009 and is also derived from U.S. Provisional Patent Application No. 61/047,268, filed on April 23, 2008, and names Robert Beelman and Michael Kalaras as co-inventors.

Pulsed UV light is a technology that delivers energy from light at a high peak power in a short amount of time. This technology results in the production by certain mushrooms of large amounts of Vitamin D2 within periods of time, varying from 1–30 seconds.

Read the Original Press Release >>

STEVENSON, Wash.–(BUSINESS WIRE)–Total Nutraceutical Solutions, Inc. (TNS) (OTCBB:TNUS) announced today that the company has launched a Nutricosmetic called Gröh for the hair and nail salon industry. Gröh is a proprietary combination of natural mushroom powders plus Vitamin D2 that has been shown to promote hair and nail growth. The Company has applied for the Gröh trademark.

The Company revealed Gröh on May 2, 2010 at the biannual internationally attended Intercoiffure America – Canada Spring Symposium held at the Fountainebleau Hotel, Miami Beach, Florida. TNS CEO, Marvin S. Hausman MD, attended this conference and gave a presentation entitled: “How Science Influences Beauty.”

Read Original Press Release >>

ScienceDaily (Jan. 7, 2008) — Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status.

Researchers studied healthy adults aged 18-84 who received either placebo, 1,000 International Units (IU) of vitamin D3, 1,000 IU of vitamin D2, or 500 IU of vitamin D2 plus 500 IU of vitamin D3 daily for three months at the end of winter to establish what effect it had on circulating levels of total 25 (OH)D as well as 25(OH)D2 and 25(OH)D3. Sixty percent of the adults were vitamin D deficient at the start of the study.

Adults who received the placebo capsule daily for three months demonstrated no significant change in their total 25(OH)D levels during the winter and early spring. Adults who ingested 1,000 vitamin D2/d gradually increased their total 25(OH)D levels during the first six weeks. Adults who ingested 1,000 IU of vitamin D3 had a baseline 25(OH)D that was statistically no different from the baselines of either the placebo group or the groups that took 1,000 IU of vitamin D2/d or 500 IU vitamin D2 plus 500 IU vitamin D3/d. The vitamin D3 group increased their serum 25(OH)D levels similar to that of the group that ingested vitamin D2.

Read Original Article >>

STEVENSON, Wash.–(BUSINESS WIRE)–Total Nutraceutical Solutions, Inc. (TNS) (OTCBB: TNUS) announced today that the company has acquired from the University of Cologne, Cologne, Germany (the “University”), an exclusive license agreement on the invention (the “Invention”) entitled “Ergothioneine Transporter,” owned by the University. The license comprises the patent application entitled “Identification of Ergothioneine Transporter and Therapeutic Uses Thereof.” This transporter is present in human cells, especially red and white blood cells, has a gene symbol SLC22A4, and can efficiently move the antioxidant L-Ergothioneine (ERGO) across cell membranes.

“Because of its dietary origin and the toxicity associated with its depletion, ET (ERGO) may represent a new vitamin whose physiologic role includes antioxidant cytoprotection.”

ERGO is a unique naturally occurring potent antioxidant that is abundant in most plants and animals. ERGO cannot be manufactured by humans and therefore is available only from dietary sources. Highest levels of ERGO are found in a number of human organ systems including liver, kidney, the eye, seminal fluid, and red blood cells. Although many plant and animal species contain Ergothioneine, only few can make it, the others absorb it from their diet, or in the case of plants, from their environment. ERGO is synthesized by mushrooms and mycobacteria in soil where it is readily absorbed by plants through their roots. The biological significance of ERGO is only now beginning to be understood; this important nutrient plays a dual role in both energy regulation and in protecting cells from oxidative damage. Inflammation and oxidative damage occur together and are associated with many human diseases including diabetes, heart disease, arthritis, fibromyalgia, Alzheimer’s disease, cancer, and even early aging.

Read Full Press Release >>

STEVENSON, Wash.–(BUSINESS WIRE)–Total Nutraceutical Solutions, Inc. (TNS) (OTCBB: TNUS) announced today that the company signed a non-exclusive agreement with Lee International Group Ltd (Lee International) to distribute TNS’s human and veterinary dietary supplements in the S.E Asian markets, including Mainland China. Lee International has years of operating experience in the S.E. Asian healthcare industry, especially in Mainland China. Lee International will advise and assist TNS in the research and development of products most suitable for this market. The market includes Mainland China, Cambodia, Vietnam, Hong Kong, and Macau. The distributor will maintain an inventory of TNS products to adequately serve the demands of the market.

“This agreement opens the door for TNS to introduce its dietary supplement portfolio of products into one of the fastest growing healthcare markets in the world,” stated Marvin S. Hausman MD, CEO, TNS. “The concept of an American company bringing organic mushroom-based supplements from the U.S. to S.E. Asia, especially China, a region long devoted to use of mushrooms to treat and prevent disease, is most intriguing.”

Read the full press release >>

Synthetic vitamin supplements are by far the most popular way to supplement our daily diet with needed nutrients.

During the manufacturing process, the organic nutrient that is considered to contain the “essential component” of a vitamin complex is synthesized in a laboratory from non food compounds such as coal tar. This is very similar to the way in which most drugs are made. One example is Thiamine Mononitrate, a B1 molecule derived from coal tar, and is labeled as B1 in nearly all of the popular “B-Complex” supplements. This factor has been linked marked reductions in male sperm counts and signs of hyperthyroid disorders.

Continue reading…

Originally Published Tuesday, February 26, 2008

Mushrooms and Vitamin D

The Mushroom Lady: Mushrooms Canada

Lately there has been alot of buzz around the issue of Mushrooms and Vitamin D. To clear up some of the questions you all might have, here is the official statement from Mushrooms Canada.

”Mushrooms and Vitamin D: A Status Report
Vitamin D Vitamin D has become the health story of the year, largely because a U.S. study* indicated that supplemental Vitamin D cuts the risk of cancer by 60 percent. Based on that evidence, the Canadian Cancer Society recommended that light-skin Canadians should obtain 1000 IU (International Units) per day during fall and winter, and dark-skin Canadians should obtain 1000 IU year-round.

Since 1920, it has been known that the main role of Vitamin D is to work with Calcium and Phosphorus to build bones strong. Recent findings suggest that Vitamin D also:
•    helps to prevent bone fractures
•    reduces the risk of diabetes in young people
•    protects against heart disease
•    reduces the risk of multiple sclerosis
•    improves lung function
The best source of Vitamin D for humans is sunlight. Subcutaneous glands in the skin use sunlight to form Pre-vitamin D which is converted to Vitamin D by the liver and kidneys. But, other factors influence our exposure to sunlight, such as distance from the equator, body coverings and age. Skin colour also affects the body’s ability to produce Vitamin D. On a bright summer day, a fair-skinned person needs less than 30 minutes to make the daily requirement of Vitamin D. A dark-skinned person may need two to three hours. Winter light, in most parts of Canada, is ineffective for Vitamin D production, and vitamin D production decreases with age.

Read Full Article>>

“The Miracle of Vitamin D”

Written by Krispin Sullivan

2000 Dec 30

In April of 2000 a clinical observation published in Archives of Internal Medicine caught my attention. Dr. Anu Prabhala and his colleagues reported on the treatment of five patients confined to wheelchairs with severe weakness and fatigue. Blood tests revealed that all suffered from severe vitamin D deficiency. The patients received 50,000 IU vitamin D per week and all became mobile within six weeks.¹

Dr. Prabhala’s research sparked my interest and led to a search for current information on vitamin D, how it works, how much we really need and how we get it. The following is a small part of the important information that I found.

Any discussion of vitamin D must begin with the discoveries of the Canadian-born dentist Weston A. Price. In his masterpiece Nutrition and Physical Degeneration, Dr. Price noted that the diet of isolated, so-called “primitive” peoples contained “at least ten times” the amount of “fat-soluble vitamins” as the standard American diet of his day.² Dr. Price determined that it was the presence of plentiful amounts of fat-soluble vitamins A and D in the diet, along with calcium, phosphorus and other minerals, that conferred such high immunity to tooth decay and resistance to disease in nonindustrialized population groups.

Today another Canadian researcher, Dr. Reinhold Vieth, argues convincingly that current vitamin D recommendations are woefully inadequate. The recommended dose of 200-400 international units (IU) will prevent rickets in children but does not come close to the optimum amount necessary for vibrant health.³ According to Dr. Vieth, the minimal daily requirement of vitamin D should be in the range of 4,000 IU from all sources, rather than the 200-400 currently suggested, or ten times the Recommended Daily Allowance (RDA). Dr. Vieth’s research perfectly matches Dr. Price’s observations of sixty years ago!

Read Full Article>>

Short-Term, High-Dose Vitamin D2 May Ease Deficiency

TUESDAY, Oct. 27 (HealthDay News) — Researchers are reporting that eight weeks of treatment with large doses of vitamin D2 can eliminate vitamin D deficiency, and twice-monthly doses can keep the condition at bay for up to six years.

The dosage — 50,000 international units (IU) every week or two — was large but did not appear to be toxic, according to the study published in the Oct. 26 issue of Archives of Internal Medicine.

Vitamin D is crucial for the body. Among its attributes, it strengthens bones by helping the body absorb calcium and phosphorus from food. Low levels of vitamin D can cause rickets in children and an adult bone disorder called osteomalacia.

A deficiency can also lead to osteoporosis, and research has suggested that it also has something to do with higher risks for such diseases as cancer, heart disease, diabetes, autoimmune diseases and flu, the study’s senior author, Dr. Michael F. Holick, director of the Bone Healthcare Clinic and the Vitamin D, Skin and Bone Research Laboratory at Boston University School of Medicine, said in a university news release.

Read Full Article

Is Vitamin D the health supplement of the year?

By:Natural Health Examiner: Genevieve Kiger

Vitamin D seems to be all the rage this year, credited with reducing the risk of an amazing array or illnesses and conditions, including osteoporosis, and perhaps even such conditions as cancer and autoimmune, cardiovascular, and infectious diseases like H1N1 swine flu.  According to a press release on November 16th by Consumer Reports Health News, “Vitamin D is shaping up to be the nutrient of the year — if not the decade.”

What is Vitamin D?

Vitamin D is known as “the sunshine vitamin”, because the primary source is synthesis of it in the body when exposed to sunlight.  However, it is also added to many dairy and grain products, multivitamins, sold alone as a dietary supplement, and is naturally occurring in a umber of fish, like herring, salmon, mackerel, sardines, and tuna.

Read Full article